Omvoh (mirikizumab) — A Lilly Medicine

For adults with moderate to severe UC or CD1

Their UC and CD goals are in reach and so are yours with Omvoh

Bowel urgency reduction. Long-term remission regardless of biologic exposure.

Reach your goals with Omvoh - an IL-23p19 antagonist for adults with moderately to severely active UC or CD1

Lasting Efficacy2,3

Ulcerative Colitis

UC: Clinical remission, endoscopic improvement, and HEMR maintained at 4 years.6,7

Crohn's Disease

CD: Clinical remission and endoscopic response maintained at 2 years.3
Consistent Efficacy Regardless of Biologic Experience1

Ulcerative Colitis

UC: Clinical remission at Week 52 in overall patients and biologic-experience subgroups (bio-naïve and bio-failure).1

Crohn's Disease

CD: Clinical remission at Week 52 in overall patients and biologic-experience subgroups (bio-naïve and bio-failure).1
Improvement in Disruptive Symptoms1,2,4,5

Ulcerative Colitis

UC: Bowel urgency improvement as early as Week 2 and sustained through 4 years.6,7

Crohn's Disease

CD: Bowel urgency improvement as early as Week 6 and sustained through 2 years.1,3,4,7
Dosing

Ulcerative Colitis

In-label flexible dosing in UC, with extended induction and re-induction.1

Crohn's Disease

Indication-optimized, with patients in mind.1
Safety Demonstrated Across Multiple Studies for Two Indications UC and CD1

Bio-failure=biologic-failure; bio-naïve=biologic-naïve; CD=Crohn's disease; HEMR=histologic endoscopic mucosal remission; IL=interleukin; UC=ulcerative colitis.

Stay in the Loop with Fresh Updates!

Learn more about how Omvoh can help your UC patients with their most burdensome symptom

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The VIVID-1 Study: understanding the long-term effects of Omvoh in active Crohn's disease

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Long-term remission up to 4 years in patients with moderately to severely active UC with Omvoh

What's New? Watch Now.

Learn more about how Omvoh can help your UC patients with their most burdensome symptom.

Prof. Marc Ferrante

VIVID-2 — key efficacy data in CD

Dr. Alissa Walsh

Patient case

Prof. Sebastian Zeissig

Patient case — bio-naïve UC

Prof. Sebastian Zeissig

Patient case — TL Experience

Dr. Tim Raine

ECCO 2024 post-congress

Prof. Vipul Jairath

CD launch burst — mirikizumab vs ustekinumab


Bio-failure = biologic-failure; bio-naïve = biologic-naïve; CD = Crohn's disease; HEMR = histologic endoscopic mucosal remission; IL = interleukin; UC = ulcerative colitis.

  1. Omvoh EUSPC FEB 2025.
  2. Sands BE, D'Haens G, Clemow DB, Irving PM, Johns JT, Gibble TH, et al. Three-year efficacy and safety of mirikizumab following 152 weeks of continuous treatment for ulcerative colitis: results from the LUCENT-3 open-label extension study. Inflammatory Bowel Diseases. Published online October 25, 2024; Epub: izae253.
  3. Barnes EL, Sands BE, D'Haens G, Hisamatsu T, Kelly CR, Lu N, et al. Long-term efficacy and safety of mirikizumab following 104 weeks of continuous treatment for Crohn's disease: VIVID-2 open-label extension study. CCC; February 6–8, 2025.
  4. Jairath V, et al. Oral presentation at: ECCO 2024. Abstract OP0550.
  5. Data on File. REF-72116. Eli Lilly and Company.
  6. Sands BE, et al. Inflamm Bowel Dis. 2025;31(7):1876–1890.
  7. Data on file, REF-75768, Eli Lilly and Company.